![]() They are effective at lowering the acidity of the stomach, in turn preventing heartburn, a burning sensation in the chest that occurs when stomach acid rises up into the esophagus. Proton-pump inhibitors, or PPIs, are among the worlds most widely prescribed drugs, with $14 billion in annual sales. ShutterstockĪ large data-mining study carried out by investigators at the Stanford University School of Medicine has linked a popular class of heartburn drugs to an elevated risk of heart attack. Stanford researchers found an association between a commonly used drug for treating heartburn and the likelihood of incurring a heart attack down the road. Some Heartburn Drugs May Boost Risk Of Heart Attack Study FindsĪ data-mining study has found an association between the use of proton-pump inhibitors, which account for 100 million prescriptions per year in the United States alone, and the likelihood of incurring a heart attack down the road. If you have been using PPIs over the counter for a long time, tell your doctor, Shah said. adults to record incidence of PPI use and of cardiovascular risk. They searched more than 16 million clinical records for almost three million U.S. ![]() The researchers used clinical notes recorded at Stanford University since 1994 and a web-based electronic health record system of mostly private practices. use one of these PPI drugs each year, he and his coauthors write in the journal PLOS ONE. Now, given the underlying biology and the effect of these drugs in reducing nitric oxide in the blood vessel walls, the observed association is not super surprising, Shah told Reuters Health by email.Īlthough the results are compelling, this study does not prove that PPIs cause heart attacks, however, he said. Shah of Stanford University in California, but most research has focused on the interaction between these drugs and the blood thinner clopidogrel. There have been questions about the safety of these drugs for people who have had a coronary event like a heart attack, said lead author Nigam H. The drugs, called proton-pump inhibitors, lower acidity in the stomach and prevent the burning sensation in the esophagus that indicates acid reflux. People who take certain popular heartburn medications, like omeprazole, are at increased risk of heart attack, according to a data mining study by U.S. Some Heartburn Drugs May Carry Heightened Risk Of Heart Attack However, individuals may often not know how to tell heartburn from a heart attack. Heart attacks involve the heart and not the esophagus or acid regurgitation.īecause the esophagus and heart are located near each other, many people consider pain in that region as a sign of either heartburn or a heart attack. Other names for heartburn include indigestion, dyspepsia, acid reflux, gastroesophageal reflux disease, pyrolysis, and even “cardialgia.”Ī heart attack often is a sudden and sometimes fatal occurrence of coronary thrombosis that frequently produces chest pain and/or additional pain that may radiate to the neck, jaw, and/or arms. Heartburn is a misnomer because it does not involve the heart. ![]() Heartburn often is caused by a malfunction in the esophageal sphincter muscle, which causes regurgitation of acid from the stomach into the esophagus. Heartburn is a symptom, and usually feels like a burning sensation in the chest, under the sternum, and in the esophagus that can extend to the neck, throat, and/or face.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |